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CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential
Anticancer Research, 36 (2016), 10; 5437-5442. https://doi.org/10.21873/anticanres.11122
Bišćanin, Alen; Ljubičić, Neven; Boban, Marko; Baličević, Drinko; Pavić, Ivana; Bišćanin, Mirela Maver; Budimir, Ivan; Dorosulic, Zdravko; Duvnjak, Marko

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Bišćanin, A., Ljubičić, N., Boban, M., Baličević, D., Pavić, I., Bišćanin, M. M. ... Duvnjak, M. (2016). CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential. Anticancer Research, 36. (10), 5437-5442. doi: 10.21873/anticanres.11122

Bišćanin, Alen, et al. "CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential." Anticancer Research, vol. 36, br. 10, 2016, str. 5437-5442. https://doi.org/10.21873/anticanres.11122

Bišćanin, Alen, Neven Ljubičić, Marko Boban, Drinko Baličević, Ivana Pavić, Mirela Maver Bišćanin, Ivan Budimir, Zdravko Dorosulic i Marko Duvnjak. "CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential." Anticancer Research 36, br. 10 (2016): 5437-5442. https://doi.org/10.21873/anticanres.11122

Bišćanin, A., et al. (2016) 'CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential', Anticancer Research, 36(10), str. 5437-5442. doi: 10.21873/anticanres.11122

Bišćanin A, Ljubičić N, Boban M, Baličević D, Pavić I, Bišćanin MM, i sur.. CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential. Anticancer Research [Internet]. 12.10.2016. [pristupljeno 28.03.2025.];36(10):5437-5442. doi: 10.21873/anticanres.11122

A. Bišćanin, et al., "CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential", Anticancer Research, vol. 36, br. 10, str. 5437-5442, Listopad 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:127405. [Citirano: 28.03.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:127405
Podaci o radu
Naslov (engleski)CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential
AutorAlen Bišćanin
AutorNeven Ljubičić
AutorMarko Boban
AutorDrinko Baličević
AutorIvana Pavić
AutorMirela Maver Bišćanin
AutorIvan Budimir
AutorZdravko Dorosulic
AutorMarko Duvnjak
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Autorova ustanova(Klinički bolnički centar Zagreb)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
Background/Aim: Colorectal cancer is a major public health problem. The adenoma-carcinoma sequence offers potential for screening and surveillance. We tested the clinical behavior and diagnostic utility of connexin 43 (CX43) in connection with pathohistological risk. Patients and Methods: Immunohistochemical expression of CX43 in colonic adenomas and surrounding mucosa from 87 patients was determined. Results: CX43 expression was higher in mucosa surrounding adenomas with high-grade dysplasia... Više (p=0.047), larger adenomas (p=0.015) and villous adenomas (p=0.02). No difference of CX43 expression in adenomas according to grade of dysplasia was found (p=0.87). CX43 expression in adenomas was dependent on the patient's hemoglobin level (p=0.002), family history of colorectal cancer (p=0.009) and statin therapy (p=0.049). Conclusion: CX43 expression in mucosa surrounding adenoma could be an additional factor indicative of malignant potential. CX43 expression in colonic adenoma seems to be closely related to family history of colorectal cancer, statin therapy and hemoglobin level. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAnticancer Research
Brojčani podacivol. 36, br. 10, str. 5437-5442
p-ISSN0250-7005
e-ISSN1791-7530
DOIhttps://doi.org/10.21873/anticanres.11122
URN:NBNurn:nbn:hr:127:127405
Datum objave publikacije2016-10-12
URL dokumentahttp://ar.iiarjournals.org/content/36/10/5437.abstract
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-10-30 08:59:03
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