prikaz prve stranice dokumenta Local drug delivery for oral mucosal diseases: challenges and opportunities
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Local drug delivery for oral mucosal diseases: challenges and opportunities
Oral Diseases, 17 (2011), s1; 73-84. https://doi.org/10.1111/j.1601-0825.2011.01793.x
Sankar, V; Hearnden, V; Hull, K; Juras, D Vidovic; Greenberg, MS; Kerr, AR; Lockhart, PB; Patton, LL; Porter, S; Thornhill, M

Institucijski repozitorij: Repozitorij stomatološkog fakulteta u Zagrebu

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Sankar, V., Hearnden, V., Hull, K., Juras, D. V., Greenberg, M., Kerr, A. ... Thornhill, M. (2011). Local drug delivery for oral mucosal diseases: challenges and opportunities. Oral Diseases, 17. (s1), 73-84. doi: 10.1111/j.1601-0825.2011.01793.x

Sankar, V, et al. "Local drug delivery for oral mucosal diseases: challenges and opportunities." Oral Diseases, vol. 17, br. s1, 2011, str. 73-84. https://doi.org/10.1111/j.1601-0825.2011.01793.x

Sankar, V, V Hearnden, K Hull, D Vidovic Juras, MS Greenberg, AR Kerr, PB Lockhart, LL Patton, S Porter i M Thornhill. "Local drug delivery for oral mucosal diseases: challenges and opportunities." Oral Diseases 17, br. s1 (2011): 73-84. https://doi.org/10.1111/j.1601-0825.2011.01793.x

Sankar, V., et al. (2011) 'Local drug delivery for oral mucosal diseases: challenges and opportunities', Oral Diseases, 17(s1), str. 73-84. doi: 10.1111/j.1601-0825.2011.01793.x

Sankar V, Hearnden V, Hull K, Juras DV, Greenberg M, Kerr A, i sur.. Local drug delivery for oral mucosal diseases: challenges and opportunities. Oral Diseases [Internet]. 08.03.2011. [pristupljeno 27.12.2024.];17(s1):73-84. doi: 10.1111/j.1601-0825.2011.01793.x

V. Sankar, et al., "Local drug delivery for oral mucosal diseases: challenges and opportunities", Oral Diseases, vol. 17, br. s1, str. 73-84, Ožujak 2011. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:528901. [Citirano: 27.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:528901
Podaci o radu
Naslov (engleski)Local drug delivery for oral mucosal diseases: challenges and opportunities
AutorV Sankar
AutorV Hearnden
AutorK Hull
AutorD Vidovic Juras
AutorMS Greenberg
AutorAR Kerr
AutorPB Lockhart
AutorLL Patton
AutorS Porter
AutorM Thornhill
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
There are few topical formulations used for oral medicine applications most of which have been developed for the management of dermatological conditions. As such, numerous obstacles are faced when utilizing these preparations in the oral cavity, namely enzymatic degradation, taste, limited surface area, poor tissue penetration and accidental swallowing. In this review, we discuss common mucosal diseases such as oral cancer, mucositis, vesiculo‐erosive conditions, infections, neuropathic pain and salivary dysfunction, which could benefit from topical delivery systems designed specifically for the oral mucosa, which are capable of sustained release. Each condition requires distinct penetration and drug retention profiles in order to optimize treatment and minimize side effects. Local drug delivery may provide a more targeted and efficient drug‐delivery option than systemic delivery for diseases of the oral mucosa. We identify those mucosal diseases currently being treated, the challenges that must be overcome and the potential of novel therapies. Novel biological therapies such as macromolecular biological drugs, peptides and gene therapy may be of value in the treatment of many chronic oral conditions and thus in oral medicine if their delivery can be optimized.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaOral Diseases
Brojčani podacivol. 17, br. s1, str. 73-84
p-ISSN1354-523X
e-ISSN1601-0825
DOIhttps://doi.org/10.1111/j.1601-0825.2011.01793.x
URN:NBNurn:nbn:hr:127:528901
Datum objave publikacije2011-03-08
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/j.1601-0825.2011.01793.x
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-10-31 10:09:02