aim of this study is to examine whether physical activity will affect motorical coordination and power for a period of four months in children with different developmental disabilities. The research was conducted at the Center for Education, Rehabilitation and Rehabilitation "Podravsko Sunce“ (The Sun of Podravina region). A group of nine children with different developmental disabilities, aged four to seven, was included. Their motorical skills (coordination and power) were measured by various motorical tests. Statistical results indicated an improvement in motorical coordination and power in some children. Children differ in physical appearance, intellectual ability, experience, skills, knowledge and behaviour. Physical activity is a vital human necessity. It is important because it affects the development of motorics, motorical skills, the level of health, and therefore the quality of life. This paper specifically focused on children with disabilities. Children with disabilities under the Convention on the Rights of Persons with Disabilities are children with long-term disabilities, which, depending on physical, social, economic or cultural barriers, may limit their ability to participate fully in society on an equal basis with others. For them, there are no specific recommendations for how to perform physical activities, but they are mostly based on recommendations for the general population of children, with adapted activities or programmes to the difficulties, health and functional status of each child.