Soft tissue sarcomas are a broad group of malignant tumors that arise from connective tissue. Tumors included in this group are fibrosarcoma, peripheral nerve sheath tumors, liposarcoma, myxosarcoma, vascular wall tumors, pleomorphic sarcoma and mesenchymoma. Despite being derived from cells of different origins, they are classified in the same group because they behave in a very similar way in terms of growth, proliferation, and response to treatment. These tumors usually occur as solitary formations in the skin and subcutaneous tissue. Formations can be soft or hard in consistency, and are mostly slow-growing. Tumors are locally invasive but rarely metastasize unless of a high degree. Diagnostic methods used for their identification are FNA, biopsy and immunohistochemical examination. FNA and histopathological examination complement each other in the diagnosis of these tumors. Pathohistological examination of the biopsy determines the degree of the tumor. Grade I includes those neoplasms whose cells are well differentiated. Grade II those that are moderately differentiated, and grade III neoplasms that are poorly differentiated. Tumor grades can predict the likelihood of metastasis and ultimately determine prognosis. Blood tests, chest x-rays, and sometimes abdominal ultrasounds are indicated to determine other tumor-related problems. More detailed diagnostic imaging, such as MR or CT, can be of great help in planning surgical removal. Excision with wide margins is the first choice in the treatment of soft tissue sarcoma. Wide margins usually mean removal of at least 3 cm of normal tissue surrounding the tumor in all directions, and these are recommended because soft tissue sarcomas often infiltrate surrounding tissue. Conducting wide margins prevents recurrence.